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Integrative metabolomic and single-cell transcriptomic analysis of recurrent condyloma acuminatum in humans

Abstract Condyloma acuminatum (CA), primarily caused by low-risk HPV6/11, is a benign proliferative disease that is difficult to cure and prone to recurrence. However, the molecular and immune mechanisms underlying relapse remain unclear. We combined metabolomic profiling with single-cell RNA sequen...

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Wedi'i Gadw mewn:
Prif Awduron: Yushu Wei, Yaohan Xu, Chenxi Feng, Siji Chen, Jie Chen, Jiacheng Wang, Jingying Pan, Yinjing Song, Chunting Hua, Miaolian Cai, Hao Cheng, Jiang Zhu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Portfolio 2026-02-01
Cyfres:Scientific Reports
Pynciau:
Condyloma acuminatum
Human papillomavirus
Recurrence
Metabolomics
Single-cell sequencing
Immunometabolism
Mynediad Ar-lein:https://doi.org/10.1038/s41598-026-37989-8
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