Antitrypanosomal Activity of Sesquiterpene Lactones from Helianthus tuberosus L. Including a New Furanoheliangolide with an Unusual Structure

As part of our efforts to exploit the antitrypanosomal potential of sesquiterpene lactones (STL) from Helianthus tuberosus L. (Asteraceae), besides the known 4,15-iso-atriplicolide tiglate, -methacrylate and -isobutyrate, a hitherto unknown STL was isolated. Its structure was solved by extensive NMR...

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Autors principals:	Anna Galkina, Nico Krause, Mairin Lenz, Constantin G. Daniliuc, Marcel Kaiser, Thomas J. Schmidt
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2019-03-01
Col·lecció:	Molecules
Matèries:	sesquiterpene lactone furanoheliangolide X-ray crystallography antiprotozoal activity Trypanosoma brucei rhodesiense Trypanosoma cruzi Leishmania donovani Plasmodium falciparum cytotoxicity
Accés en línia:	http://www.mdpi.com/1420-3049/24/6/1068
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