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The Dynamic Entropy of Tumor Immune Infiltrates: The Impact of Recirculation, Antigen-Specific Interactions, and Retention on T Cells in Tumors

Analysis of tumor infiltration using conventional methods reveals a snapshot view of lymphocyte interactions with the tumor environment. However, lymphocytes have the unique capacity for continued recirculation, exploring varied tissues for the presence of cognate antigens according to inflammatory...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Tiffany C. Blair, Alejandro F. Alice, Lauren Zebertavage, Marka R. Crittenden, Michael J. Gough
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-04-01
Schriftenreihe:Frontiers in Oncology
Schlagworte:
T cell
recirculation
tumor
clonality analysis
retention
recruitment
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fonc.2021.653625/full
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