Myeloid MyD88 restricts CD8+ T cell response to radiation therapy in pancreatic cancer

Abstract Radiation therapy induces immunogenic cell death in cancer cells, whereby released endogenous adjuvants are sensed by immune cells to direct adaptive immune responses. TLRs expressed on several immune subtypes recognize innate adjuvants to direct downstream inflammatory responses in part vi...

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Hlavní autoři:	Terry R. Medler, Tiffany C. Blair, Alejandro F. Alice, Alexa K. Dowdell, Brian D. Piening, Marka R. Crittenden, Michael J. Gough
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2023-05-01
Edice:	Scientific Reports
On-line přístup:	https://doi.org/10.1038/s41598-023-35834-w
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