LAG3 (LAG-3, CD223) DNA methylation correlates with LAG3 expression by tumor and immune cells, immune cell infiltration, and overall survival in clear cell renal cell carcinoma

Background Lymphocyte activating 3 (LAG3, LAG-3, CD223) is a promising target for immune checkpoint inhibition in clear cell renal cell carcinoma (KIRC). The aim of this study was to investigate the epigenetic regulation of LAG3 in KIRC by methylation.Methods We correlated quantitative LAG3 methylat...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Dimo Dietrich, Niklas Klümper, Damian J Ralser, Emma Grace Bawden, Jenny Landsberg, Romina Zarbl, Glen Kristiansen, Marieta Toma, Manuel Ritter, Michael Hölzel, Jörg Ellinger
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMJ Publishing Group 2020-05-01
Цуврал:	Journal for ImmunoTherapy of Cancer
Онлайн хандалт:	https://jitc.bmj.com/content/8/1/e000552.full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!