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Investigating Apoptozole as a Chemical Probe for HSP70 Inhibition.

The use of chemical tools to validate clinical targets has gained in popularity over recent years and the importance of understanding the activity, selectivity and mechanism of action of these compounds is well recognized. Dysregulation of the HSP70 protein family has been linked to multiple cancer...

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Detalhes bibliográficos
Principais autores: Lindsay E Evans, Matthew D Cheeseman, Norhakim Yahya, Keith Jones
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-01-01
coleção:PLoS ONE
Acesso em linha:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0140006&type=printable
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