Rad5 and Its Human Homologs, HLTF and SHPRH, Are Novel Interactors of Mismatch Repair

DNA mismatch repair (MMR) repairs replication errors, and MMR defects play a role in both inherited cancer predisposition syndromes and in sporadic cancers. MMR also recognizes mispairs caused by environmental and chemotherapeutic agents; however, in these cases mispair recognition leads to apoptosi...

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Hlavní autoři:	Anna K. Miller, Guogen Mao, Breanna G. Knicely, Hannah G. Daniels, Christine Rahal, Christopher D. Putnam, Richard D. Kolodner, Eva M. Goellner
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-06-01
Edice:	Frontiers in Cell and Developmental Biology
Témata:	mismatch repair (MMR) rad5 SHPRH HLTF alkylating agent MNNG binding motif
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fcell.2022.843121/full
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