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The calcium-sensing receptor modulates the prostaglandin E2 pathway in intestinal inflammation

Introduction: The prostaglandin E2 (PGE2) pathway is one of the main mediators of intestinal inflammation. As activation of the calcium-sensing receptor (CaSR) induces expression of inflammatory markers in the colon, we assessed the impact of the CaSR on the PGE2 pathway regulation in colon cancer c...

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Principais autores: Valeriya Gushchina, Nadja Kupper, Michael Schwarzkopf, Gitta Frisch, Karina Piatek, Cornelia Aigner, Alexandra Michel, Hemma Schueffl, Luca Iamartino, Taha Elajnaf, Teresa Manhardt, Andrea Vlasaty, Petra Heffeter, Marcella Bassetto, Enikö Kállay, Martin Schepelmann
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-04-01
Serier:Frontiers in Pharmacology
Fag:
calcium-sensing receptor (CaSR)
prostaglandins
inflammation
colitis
calcimimetic
calcilytic
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2023.1151144/full
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