The calcium-sensing receptor modulates the prostaglandin E2 pathway in intestinal inflammation

Introduction: The prostaglandin E2 (PGE2) pathway is one of the main mediators of intestinal inflammation. As activation of the calcium-sensing receptor (CaSR) induces expression of inflammatory markers in the colon, we assessed the impact of the CaSR on the PGE2 pathway regulation in colon cancer c...

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Principais autores:	Valeriya Gushchina, Nadja Kupper, Michael Schwarzkopf, Gitta Frisch, Karina Piatek, Cornelia Aigner, Alexandra Michel, Hemma Schueffl, Luca Iamartino, Taha Elajnaf, Teresa Manhardt, Andrea Vlasaty, Petra Heffeter, Marcella Bassetto, Enikö Kállay, Martin Schepelmann
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2023-04-01
Series:	Frontiers in Pharmacology
Assuntos:	calcium-sensing receptor (CaSR) prostaglandins inflammation colitis calcimimetic calcilytic
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1151144/full
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