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Clinical cell-surface targets in metastatic and primary solid cancers

Therapies against cell-surface targets (CSTs) represent an emerging treatment class in solid malignancies. However, high-throughput investigations of CST expression across cancer types have been reliant on data sets of mostly primary tumors, despite therapeutic use most commonly in metastatic diseas...

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Principais autores: Marina N. Sharifi, Yue Shi, Matthew R. Chrostek, S. Carson Callahan, Tianfu Shang, Tracy J. Berg, Kyle T. Helzer, Matthew L. Bootsma, Martin Sjöström, Andreas Josefsson, Felix Y. Feng, Laura B. Huffman, Chris Schulte, Grace C. Blitzer, Quaovi H. Sodji, Zachary S. Morris, Vincent T. Ma, Labros Meimetis, David Kosoff, Amy K. Taylor, Aaron M. LeBeau, Joshua M. Lang, Shuang G. Zhao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical investigation 2024-09-01
coleção:JCI Insight
Assuntos:
Oncology
Acesso em linha:https://doi.org/10.1172/jci.insight.183674
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