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Personalizing voriconazole dosing in Chinese hematological patients: CYP2C19 phenotype and albumin-bilirubin grade as key predictors of trough concentrations

PurposeThis retrospective, single-center study aimed to evaluate the genetic and non-genetic factors influencing voriconazole (VRC) trough concentration (Ctrough), efficacy and safety in hematological patients.MethodsMedical records of inpatients were reviewed retrospectively. Univariate and multiva...

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書誌詳細
主要な著者: Lin Hu, Xi Tang, Yanfei Li, Juanjuan Huang
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2025-10-01
シリーズ:Frontiers in Pharmacology
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オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fphar.2025.1667461/full
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