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Enhanced therapeutic window for antimicrobial Pept-ins by investigating their structure-activity relationship.

The overconsumption and inappropriate use of antibiotics is escalating antibiotic resistance development, which is now one of the 10 top threats to global health. Introducing antibiotics with a novel mode of action into clinical use is urgently needed to address this issue. Deliberately inducing agg...

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Hlavní autoři: Guiqin Wu, Laleh Khodaparast, Ladan Khodaparast, Matthias De Vleeschouwer, Nikolaos Louros, Rodrigo Gallardo, Pengpeng Yi, Frederic Rousseau, Joost Schymkowitz
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2023-01-01
Edice:PLoS ONE
On-line přístup:https://doi.org/10.1371/journal.pone.0283674
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