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HMGB1 promotes chemoresistance in small cell lung cancer by inducing PARP1-related nucleophagy

Introduction: Small cell lung cancer (SCLC) is prone to chemoresistance, which is closely related to genome homeostasis-related processes, such as DNA damage and repair. Nucleophagy is the elimination of specific nuclear substances by cells themselves and is responsible for maintaining genome and ch...

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Principais autores: Weitao Shen, Qiong Lyu, Ruibin Yi, Yueqin Sun, Wei Zhang, Ting Wei, Yueming Zhang, Jian Shi, Jian Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-12-01
Serier:Journal of Advanced Research
Fag:
High-mobility group box protein B1 (HMGB1)
Small cell lung cancer
Nucleophagy
PARP1
PARP inhibitors
Online adgang:http://www.sciencedirect.com/science/article/pii/S2090123223004071
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