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Exploring the radiochemistry of PARP inhibitors: a new era in therapy and imaging

Abstract Background Poly (ADP-ribose) polymerase (PARP) inhibitors have emerged as a promising class of therapeutics, particularly in the treatment of cancers with defective DNA repair mechanisms, such as those with breast cancer genes (BRCA) mutations. Their effectiveness in cancer therapy is now w...

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主要な著者: Gianluca Destro, Rebecca Rizzo, Chiara Rua, Raha Rouhbakhsh Azimi, Silvia Morbelli
フォーマット: Artigo
言語:Inglês
出版事項: SpringerOpen 2025-07-01
シリーズ:EJNMMI Radiopharmacy and Chemistry
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オンライン・アクセス:https://doi.org/10.1186/s41181-025-00364-5
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