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Post-Transcriptional Regulation of PARP7 Protein Stability Is Controlled by Androgen Signaling

Poly-ADP-ribose polymerases (PARPs) are enzymes that catalyze ADP-ribosylation and play critical roles in normal and disease settings. The PARP family member, PARP7, is a mono-ADP-ribosyltransferase that has been suggested to play a tumor suppressive role in breast, ovarian, and colorectal cancer. H...

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Principais autores: Teddy Kamata, Chun-Song Yang, Tiffany A. Melhuish, Henry F. Frierson Jr., David Wotton, Bryce M. Paschal
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-02-01
Serier:Cells
Fag:
ADP-ribosylation
mono-ADP-ribosyltransferase
PARP7
ARTD14
TIPARP
androgen receptor
Online adgang:https://www.mdpi.com/2073-4409/10/2/363
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