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ER Stress and Unfolded Protein Response in Leukemia: Friend, Foe, or Both?

The unfolded protein response (UPR) is an evolutionarily conserved adaptive signaling pathway triggered by a stress of the endoplasmic reticulum (ER) lumen compartment, which is initiated by the accumulation of unfolded proteins. This response, mediated by three sensors-Inositol Requiring Enzyme 1 (...

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Hlavní autoři: Kelly Féral, Manon Jaud, Céline Philippe, Doriana Di Bella, Stéphane Pyronnet, Kevin Rouault-Pierre, Laurent Mazzolini, Christian Touriol
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2021-01-01
Edice:Biomolecules
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On-line přístup:https://www.mdpi.com/2218-273X/11/2/199
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