ER Stress and Unfolded Protein Response in Leukemia: Friend, Foe, or Both?

The unfolded protein response (UPR) is an evolutionarily conserved adaptive signaling pathway triggered by a stress of the endoplasmic reticulum (ER) lumen compartment, which is initiated by the accumulation of unfolded proteins. This response, mediated by three sensors-Inositol Requiring Enzyme 1 (...

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Principais autores:	Kelly Féral, Manon Jaud, Céline Philippe, Doriana Di Bella, Stéphane Pyronnet, Kevin Rouault-Pierre, Laurent Mazzolini, Christian Touriol
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-01-01
Series:	Biomolecules
Assuntos:	endoplasmic reticulum stress unfolded protein response (UPR) leukemia AML CLL ALL
Acceso en liña:	https://www.mdpi.com/2218-273X/11/2/199
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