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Generation of ectodysplasin a (eda)-targeted knockout zebrafish via the crispr/cas9 system

Ectodysplasin A (EDA) plays a vital role in the development of skin appendages, especially in fish scales. Zebrafish model with the mutation of eda was found using CRISPR/Cas9 system. CRISPR/Cas9 nucleases targeting to two loci in exon 4 of eda, were constructed and injected into zebrafish embryos,...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Cunfang ZHANG, Linyong HU, Sijia LIU, Wen WANG, Kai ZHAO
Format: Artigo
Sprache:Inglês
Veröffentlicht: Kafkas University, Faculty of Veterinary Medicine 2020-01-01
Schriftenreihe:Kafkas Universitesi Veteriner Fakültesi Dergisi
Schlagworte:
gene knockout
eda
zebrafish mutant
scale loss
Online-Zugang:https://vetdergikafkas.org/pdf.php?id=2677
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