Knockout and phenotype analysis of lkb1 gene in zebrafish by CRISPR/Cas9 technology
Objective To knock out lkb1 gene in zebrafish by CRISPR/Cas9 technique, observe and verify homozygote phenotype, and preliminarily explore the effect of lkb1 on the development of renal tubule. Methods The gRNA targeting lkb1gene was designed and synthesized. The gRNA and Cas9 mRNA were injected int...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Chinês |
| Publicado em: |
Editorial Office of Journal of Third Military Medical University
2019-08-01
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| Colecção: | Di-san junyi daxue xuebao |
| Assuntos: | |
| Acesso em linha: | http://aammt.tmmu.edu.cn/Upload/rhtml/201902114.htm |
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