Decoding circulating neutrophil phenotypes in triple-negative breast cancer via optimized single-cell RNA sequencing

Abstract Neutrophils are emerging as key regulators of tumor biology, influencing cancer progression, immune evasion, and therapeutic response. However, their transcriptomic characterization remains challenging due to low RNA content, limiting confident discrimination from other leukocyte population...

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Hauptverfasser:	Marcin Banacki, Krzysztof Pastuszak, Michał Sieczyński, Grażyna Suchodolska, Elżbieta Senkus, Iwona Inkielewicz-Stepniak, Anna Supernat, Anna Żaczek
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Springer 2026-05-01
Schriftenreihe:	Cancer Immunology, Immunotherapy
Schlagworte:	Neutrophils Breast cancer Neutrophil identification Single-cell RNA sequencing
Online-Zugang:	https://doi.org/10.1007/s00262-026-04345-8
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