Interplay between red blood cells and circulating tumor cells: clinical and molecular evidence of a putative pro-metastatic axis

Abstract Recent evidence suggests that red blood cells (RBCs) may actively regulate course of tumor disease, whereas red cell distribution width (RDW) might even serve as surrogate marker of tumor progression. Here, we investigated the clinical and molecular significance of RDW in breast (BrCa) and...

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Principais autores:	Julia Richert, Marta Popęda, Anna Muchlińska, Robert Wenta, Barbara Bollin-Matysiak, Aleksandra Parteka, Beata Pieczyńska-Uziębło, Tomasz Kryczka, Anna Żaczek, Grażyna Suchodolska, Elżbieta Senkus, Marcin Matuszewski, Kevin Miszewski, Natalia Bednarz-Knoll
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-11-01
Series:	Journal of Translational Medicine
Assuntos:	Red blood cells Red blood cells distribution width Circulating tumor cells Imaging flow cytometry Tumor progression Breast cancer
Acceso en liña:	https://doi.org/10.1186/s12967-025-07255-y
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