Sld3CBD–Cdc45 structural insights into Cdc45 recruitment for CMG complex formation during DNA replication
DNA replication requires recruitment of Cdc45 and GINS into the MCM double hexamer by initiation factors to form an active helicase, the Cdc45–MCM–GINS (CMG) complex, at the replication origins. The initiation factor Sld3 is a central regulator of Cdc45 and GINS recruitment, working with Sld7 togeth...
Збережено в:
| Автори: | , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
eLife Sciences Publications Ltd
2025-09-01
|
| Серія: | eLife |
| Предмети: | |
| Онлайн доступ: | https://elifesciences.org/articles/101717 |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|