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BIITE: A Tool to Determine HLA Class II Epitopes from T Cell ELISpot Data.

Activation of CD4+ T cells requires the recognition of peptides that are presented by HLA class II molecules and can be assessed experimentally using the ELISpot assay. However, even given an individual's HLA class II genotype, identifying which class II molecule is responsible for a positive ELISpo...

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Bibliografiske detaljer
Principais autores: Lies Boelen, Patrick K O'Neill, Kathryn J Quigley, Catherine J Reynolds, Bernard Maillere, John H Robinson, Ganjana Lertmemongkolchai, Daniel M Altmann, Rosemary J Boyton, Becca Asquith
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2016-03-01
Serier:PLoS Computational Biology
Online adgang:https://doi.org/10.1371/journal.pcbi.1004796
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