Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions

We explored the relationship between ubiquitin proteasome system (UPS) and lysosomal markers and the formation of α-synuclein (α-syn) inclusions in nigral neurons in Parkinson disease (PD). Lysosome Associated Membrane Protein 1(LAMP1), Cathepsin D (CatD), and Heat Shock Protein73 (HSP73) immunoreac...

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Bibliografski detalji

Glavni autori:	Yaping Chu, Hemraj Dodiya, Patrick Aebischer, C. Warren Olanow, Jeffrey H. Kordower
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2009-09-01
Serija:	Neurobiology of Disease
Teme:	Parkinson's disease Lysosome Proteasome Alpha-synuclein
Online pristup:	http://www.sciencedirect.com/science/article/pii/S0969996109001351
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