Current Evidence for a Bidirectional Loop Between the Lysosome and Alpha-Synuclein Proteoforms
Cumulative evidence collected in recent decades suggests that lysosomal dysfunction contributes to neurodegenerative diseases, especially if amyloid proteins are involved. Among these, alpha-synuclein (aSyn) that progressively accumulates and aggregates in Lewy bodies is undisputedly a main culprit...
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| Автори: | , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Frontiers Media S.A.
2020-11-01
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| Серія: | Frontiers in Cell and Developmental Biology |
| Предмети: | |
| Онлайн доступ: | https://www.frontiersin.org/articles/10.3389/fcell.2020.598446/full |
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