Adipose tissue protects against sepsis-induced muscle weakness in mice: from lipolysis to ketones

Abstract Background ICU-acquired weakness is a debilitating consequence of prolonged critical illness that is associated with poor outcome. Recently, premorbid obesity has been shown to protect against such illness-induced muscle wasting and weakness. Here, we hypothesized that this protection was d...

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Hlavní autoři:	Chloë Goossens, Ruben Weckx, Sarah Derde, Thomas Dufour, Sarah Vander Perre, Lies Pauwels, Steven E. Thiessen, Paul P. Van Veldhoven, Greet Van den Berghe, Lies Langouche
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2019-07-01
Edice:	Critical Care
Témata:	Adipose tissue Skeletal muscle Sepsis Metabolism Muscle weakness
On-line přístup:	http://link.springer.com/article/10.1186/s13054-019-2506-6
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