Aloperine targets lysosomes to inhibit late autophagy and induces cell death through apoptosis and paraptosis in glioblastoma

Abstract Glioblastoma (GBM) is an aggressive intracranial tumour, and current chemotherapy regimens have limited efficacy. Aloperine (ALO), a natural alkaline compound, has shown potential as an antitumor agent. However, the effect of ALO against GBM remains unclear. This study aimed to investigate...

Descripció completa

Dades bibliogràfiques

Autors principals:	Ting Tang, Hui Liang, Wuting Wei, Yanling Han, Liang Cao, Zixiang Cong, Shiqiao Luo, Handong Wang, Meng-Liang Zhou
Format:	Artigo
Idioma:	Inglês
Publicat:	Springer 2023-11-01
Col·lecció:	Molecular Biomedicine
Matèries:	Aloperine Glioblastoma Autophagy Lysosome Paraptosis
Accés en línia:	https://doi.org/10.1186/s43556-023-00155-x
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!