α‐Hederin induces paraptosis by targeting GPCRs to activate Ca2+/MAPK signaling pathway in colorectal cancer

Abstract Background Non‐apoptotic cell death is presently emerging as a potential direction to overcome the apoptosis resistance of cancer cells. In the current study, a natural plant agent α‐hederin (α‐hed) induces caspase‐independent paraptotic modes of cell death. Purpose The present study is aim...

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Hlavní autoři:	Xiwu Rao, Ziwen Li, Qinchang Zhang, Yueyang Lai, Jianrong Liu, Liu Li, Haibo Cheng, Weixing Shen, Dongdong Sun
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2024-04-01
Edice:	Cancer Medicine
Témata:	calcium colorectal cancer MAPK paraptosis α‐Hederin
On-line přístup:	https://doi.org/10.1002/cam4.7202
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