The deubiquitinating enzyme UCHL1 is a favorable prognostic marker in neuroblastoma as it promotes neuronal differentiation

Abstract Background Neuroblastoma (NB) is the most common pediatric solid tumor that originates from neural crest-derived sympathoadrenal precursor cells that are committed to development of sympathetic nervous system. The well differentiated histological phenotype of NB tumor cells has been reporte...

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Hauptverfasser:	Yuting Gu, Fan Lv, Mingxing Xue, Kai Chen, Cheng Cheng, Xinyuan Ding, Min Jin, Guofeng Xu, Yanyun Zhang, Zhixiang Wu, Leizhen Zheng, Yeming Wu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2018-10-01
Schriftenreihe:	Journal of Experimental & Clinical Cancer Research
Schlagworte:	Neuroblastoma UCHL1 Prognosis Neural differentiation Proliferation
Online-Zugang:	http://link.springer.com/article/10.1186/s13046-018-0931-z
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