In the quest for new targets for pathogen eradication: the adenylosuccinate synthetase from the bacterium Helicobacter pylori

Adenylosuccinate synthetase (AdSS) is an enzyme at regulatory point of purine metabolism. In pathogenic organisms which utilise only the purine salvage pathway, AdSS asserts itself as a promising drug target. One of these organisms is Helicobacter pylori, a wide-spread human pathogen involved in the...

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Autors principals:	Ante Bubić, Natalia Mrnjavac, Igor Stuparević, Marta Łyczek, Beata Wielgus-Kutrowska, Agnieszka Bzowska, Marija Luić, Ivana Leščić Ašler
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis Group 2018-01-01
Col·lecció:	Journal of Enzyme Inhibition and Medicinal Chemistry
Matèries:	Helicobacter pylori adenylosuccinate synthetase enzyme kinetics enzyme inhibition oligomeric state analytical ultracentrifugation
Accés en línia:	http://dx.doi.org/10.1080/14756366.2018.1506773
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