Collagen induces activation of DDR1 through lateral dimer association and phosphorylation between dimers
The collagen-binding receptor tyrosine kinase DDR1 (discoidin domain receptor 1) is a drug target for a wide range of human diseases, but the molecular mechanism of DDR1 activation is poorly defined. Here we co-expressed different types of signalling-incompetent DDR1 mutants (‘receiver’) with functi...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
eLife Sciences Publications Ltd
2017-06-01
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| Saila: | eLife |
| Gaiak: | |
| Sarrera elektronikoa: | https://elifesciences.org/articles/25716 |
| Etiketak: |
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