Quick assessment for systematic test statistic inflation/deflation due to null model misspecifications in genome-wide environment interaction studies.

Gene-environment (GxE) interaction is one potential explanation for the missing heritability problem. A popular approach to genome-wide environment interaction studies (GWEIS) is based on regression models involving interactions between genetic variants and environment variables. Unfortunately, GWEI...

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Dades bibliogràfiques

Autors principals:	Masao Ueki, Masahiro Fujii, Gen Tamiya, for Alzheimer’s Disease Neuroimaging Initiative and the Alzheimer’s Disease Metabolomics Consortium
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2019-01-01
Col·lecció:	PLoS ONE
Accés en línia:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0219825&type=printable
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