Quick assessment for systematic test statistic inflation/deflation due to null model misspecifications in genome-wide environment interaction studies.
Gene-environment (GxE) interaction is one potential explanation for the missing heritability problem. A popular approach to genome-wide environment interaction studies (GWEIS) is based on regression models involving interactions between genetic variants and environment variables. Unfortunately, GWEI...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science (PLoS)
2019-01-01
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| Schriftenreihe: | PLoS ONE |
| Online-Zugang: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0219825&type=printable |
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