MicroRNA-1296 inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting SRPK1-mediated PI3K/AKT pathway

Abstract Background Increasing evidences demonstrate that miRNAs contribute to development and progression of hepatocellular carcinoma (HCC). Underexpression of miR-1296 is recently reported to promote growth and metastasis of human cancers. However, the expression and role of miR-1296 in HCC remain...

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Автори:	Qiuran Xu, Xin Liu, Zhikui Liu, Zhenyu Zhou, Yufeng Wang, Jianfeng Tu, Lijie Li, Hangxing Bao, Liu Yang, Kangsheng Tu
Формат:	Artigo
Мова:	Inglês
Опубліковано:	BMC 2017-06-01
Серія:	Molecular Cancer
Предмети:	MicroRNA-1296 Hepatocellular carcinoma SRPK1 Metastasis PI3K/AKT pathway
Онлайн доступ:	http://link.springer.com/article/10.1186/s12943-017-0675-y
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