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MicroRNA-1296 inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting SRPK1-mediated PI3K/AKT pathway

Abstract Background Increasing evidences demonstrate that miRNAs contribute to development and progression of hepatocellular carcinoma (HCC). Underexpression of miR-1296 is recently reported to promote growth and metastasis of human cancers. However, the expression and role of miR-1296 in HCC remain...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Qiuran Xu, Xin Liu, Zhikui Liu, Zhenyu Zhou, Yufeng Wang, Jianfeng Tu, Lijie Li, Hangxing Bao, Liu Yang, Kangsheng Tu
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2017-06-01
Rangatū:Molecular Cancer
Ngā marau:
MicroRNA-1296
Hepatocellular carcinoma
SRPK1
Metastasis
PI3K/AKT pathway
Urunga tuihono:http://link.springer.com/article/10.1186/s12943-017-0675-y
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