QR Code

In Silico Analysis of Tetrodotoxin Binding in Voltage-Gated Sodium Ion Channels from Toxin-Resistant Animal Lineages

Multiple animal species have evolved resistance to the neurotoxin tetrodotoxin (TTX) through changes in voltage-gated sodium ion channels (VGSCs). Amino acid substitutions in TTX-resistant lineages appear to be positionally convergent with changes in homologous residues associated with reductions in...

Full description

Saved in:
Main Authors: Shana L. Geffeney, Jennie Ann Cordingley, Kenyon Mitchell, Charles T. Hanifin
Format: Artigo
Language:Inglês
Published: MDPI AG 2022-11-01
Series:Marine Drugs
Subjects:
marine toxin
voltage-gated ion channels
structure
tetrodotoxin
TTX
toxin resistance
Online Access:https://www.mdpi.com/1660-3397/20/11/723
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items