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Role of Argininosuccinate Synthase 1 ‐Dependent L‐Arginine Biosynthesis in the Protective Effect of Endothelial Sirtuin 3 Against Atherosclerosis

Abstract Atherosclerosis is initiated with endothelial cell (EC) dysfunction and vascular inflammation under hyperlipidemia. Sirtuin 3 (SIRT3) is a mitochondrial deacetylase. However, the specific role of endothelial SIRT3 during atherosclerosis remains poorly understood. The present study aims to s...

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Bibliografske podrobnosti
Principais autores: Xiaoyun Cao, Vivian Wei Yan Wu, Yumeng Han, Huiling Hong, Yalan Wu, Alice Pik Shan Kong, Kathy O Lui, Xiao Yu Tian
Format: Artigo
Jezik:Inglês
Izdano: Wiley 2024-03-01
Serija:Advanced Science
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Online dostop:https://doi.org/10.1002/advs.202307256
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