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Perspectives of Positively Charged Nanocrystals of Tedizolid Phosphate as a Topical Ocular Application in Rabbits

The aim of this study was the successful utilization of the positively charged nanocrystals (NCs) of Tedizolid Phosphate (TZP) (0.1% <i>w</i>/<i>v</i>) for topical ocular applications. TZP belongs to the 1, 3-oxazolidine-2-one class of antibiotics and has therapeutic potential for the treatment of m...

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Autori principali: Abdullah Alshememry, Musaed Alkholief, Mohd Abul Kalam, Mohammad Raish, Raisuddin Ali, Sulaiman S. Alhudaithi, Muzaffar Iqbal, Aws Alshamsan
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-07-01
Serie:Molecules
Soggetti:
tedizolid
antimicrobial
nanocrystals
eyeirritation
ocular pharmacokinetics
transcorneal permeation
Accesso online:https://www.mdpi.com/1420-3049/27/14/4619
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