Fabrication and Characterization of Tedizolid Phosphate Nanocrystals for Topical Ocular Application: Improved Solubilization and In Vitro Drug Release

Positively charged NCs of TZP (0.1%, <i>w</i>/<i>v</i>) for ocular use were prepared by the antisolvent precipitation method. TZP is a novel 5-Hydroxymethyl-Oxazolidinone class of antibiotic and is effective against many drug-resistant bacterial infections. Even the phosphate salt of this drug is po...

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Principais autores:	Mohd Abul Kalam, Muzaffar Iqbal, Abdullah Alshememry, Musaed Alkholief, Aws Alshamsan
格式:	Artigo
语言:	Inglês
出版:	MDPI AG 2022-06-01
丛编:	Pharmaceutics
主题:	tedizolid phosphate nanocrystals thermal characterization in vitro release stability
在线阅读:	https://www.mdpi.com/1999-4923/14/7/1328
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