Development of New Antimycobacterial Sulfonyl Hydrazones and 4-Methyl-1,2,3-thiadiazole-Based Hydrazone Derivatives

Fifteen 4-methyl-1,2,3-thiadiazole-based hydrazone derivatives <b>3a</b>–<b>d</b> and sulfonyl hydrazones <b>5a</b>–<b>k</b> were synthesized. They were characterized by ¹H-NMR, ¹³C NMR, and HRMS. <i>Mycobacterium tuberculosis</i> strain H37Rv was used to assess their antimycob...

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Detalhes bibliográficos

Principais autores:	Violina T. Angelova, Tania Pencheva, Nikolay Vassilev, Elena K-Yovkova, Rositsa Mihaylova, Boris Petrov, Violeta Valcheva
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-04-01
coleção:	Antibiotics
Assuntos:	antimycobacterial activity ADME/Tox predictions cytotoxicity hydrazide-hydrazone derivatives sulfonyl hydrazone derivatives molecular docking
Acesso em linha:	https://www.mdpi.com/2079-6382/11/5/562
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