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Dimerization of ADAR1 modulates site-specificity of RNA editing

Abstract Adenosine-to-inosine editing is catalyzed by adenosine deaminases acting on RNA (ADARs) in double-stranded RNA (dsRNA) regions. Although three ADARs exist in mammals, ADAR1 is responsible for the vast majority of the editing events and acts on thousands of sites in the human transcriptome....

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Bibliografski detalji
Glavni autori: Allegra Mboukou, Vinod Rajendra, Serafina Messmer, Therese C. Mandl, Marjorie Catala, Carine Tisné, Michael F. Jantsch, Pierre Barraud
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2024-11-01
Serija:Nature Communications
Online pristup:https://doi.org/10.1038/s41467-024-53777-2
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