RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer
Abstract Background Runt-related transcription factor 1 (RUNX1) plays the roles of an oncogene and an anti-oncogene in epithelial tumours, and abnormally elevated RUNX1 has been suggested to contribute to the carcinogenesis of colorectal cancer (CRC). However, the mechanism remains unclear. Methods...
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| Autors principals: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2019-08-01
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| Col·lecció: | Journal of Experimental & Clinical Cancer Research |
| Matèries: | |
| Accés en línia: | http://link.springer.com/article/10.1186/s13046-019-1330-9 |
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