CAMKKβ supports growth and viability of epithelial ovarian cancer in vitro and in vivo

Abstract Epithelial ovarian cancer (EOC) metastasizes predominantly through multicellular aggregates known as spheroids, which disseminate within the peritoneal cavity and initiate secondary disease upon reattachment at distant sites. EOC spheroids resist detachment-induced cell death by upregulatin...

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Principais autores:	Matthew J. Borrelli, Adrian Buensuceso, Yudith Ramos Valdes, Tiffany P.A. Johnston, Jacob Haagsma, Trevor G. Shepherd
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2025-07-01
Serija:	Scientific Reports
Teme:	Epithelial ovarian cancer Spheroid Metastasis CAMKK2 AMPK Autophagy
Online dostop:	https://doi.org/10.1038/s41598-025-11584-9
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