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Human Rotaviruses of Multiple Genotypes Acquire Conserved VP4 Mutations during Serial Passage

Human rotaviruses exhibit limited tropism and replicate poorly in most cell lines. Attachment protein VP4 is a key rotavirus tropism determinant. Previous studies in which human rotaviruses were adapted to cultured cells identified mutations in VP4. However, most such studies were conducted using on...

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Bibliografische gegevens
Hoofdauteurs: Maximilian H. Carter, Jennifer Gribble, Julia R. Diller, Mark R. Denison, Sara A. Mirza, James D. Chappell, Natasha B. Halasa, Kristen M. Ogden
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2024-06-01
Reeks:Viruses
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Online toegang:https://www.mdpi.com/1999-4915/16/6/978
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