Combined inhibition of polyamine biosynthesis and uptake blocks Candida albicans virulence
ABSTRACT Polyamines, small organic polycations, are essential for life, and cells maintain polyamines via synthesis and uptake. Recently, we identified Hol1 as the high-affinity polyamine transporter in Saccharomyces cerevisiae. Hol1 is a conserved fungal-specific transporter with Candida albicans h...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2026-01-01
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| Colecção: | mBio |
| Assuntos: | |
| Acesso em linha: | https://journals.asm.org/doi/10.1128/mbio.03524-25 |
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