Disulfide stoppered polyrotaxanes with enhanced cellular uptake and intracellular cyclodextrin release

Background and Aim: Polyrotaxanes are molecular necklaces composed of polymers, threaded macrocycles, and bulky stopper molecules to inhibit the decomposition of the first two. These supramolecular assemblies are promising active ingredients for treating lysosomal storage disorders. This study aimed...

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Hlavní autoři:	Gergely Kali, Alexander H. Mayer, Dennis To, Martyna Truszkowska, Raphael Plangger, Markus Gallei, Andreas Bernkop-Schnürch
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-12-01
Edice:	Carbohydrate Polymer Technologies and Applications
Témata:	Cyclodextrin Poly(ethylene glycol) Polyrotaxane Cellular uptake Disulfide stopper molecules
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S266689392400166X
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