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Disulfide stoppered polyrotaxanes with enhanced cellular uptake and intracellular cyclodextrin release

Background and Aim: Polyrotaxanes are molecular necklaces composed of polymers, threaded macrocycles, and bulky stopper molecules to inhibit the decomposition of the first two. These supramolecular assemblies are promising active ingredients for treating lysosomal storage disorders. This study aimed...

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Autori principali: Gergely Kali, Alexander H. Mayer, Dennis To, Martyna Truszkowska, Raphael Plangger, Markus Gallei, Andreas Bernkop-Schnürch
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2024-12-01
Serie:Carbohydrate Polymer Technologies and Applications
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Accesso online:http://www.sciencedirect.com/science/article/pii/S266689392400166X
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