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Neonatal Alcohol Exposure in Mice Induces Select Differentiation- and Apoptosis-Related Chromatin Changes Both Independent of and Dependent on Sex

Prenatal alcohol exposure (PAE) affects many aspects of physiology and behavior, including brain development. Specifically, ethanol can influence expression of genes important for brain growth, including chromatin modifiers. Ethanol can also increase apoptotic cell death in the brain and alter epige...

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Principais autores: Samantha L. Schaffner, Alexandre A. Lussier, Jessica A. Baker, Dan Goldowitz, Kristin M. Hamre, Michael S. Kobor
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-02-01
Serier:Frontiers in Genetics
Fag:
neonatal alcohol exposure
epigenetics
chromatin
apoptosis
sex differences
Online adgang:https://www.frontiersin.org/article/10.3389/fgene.2020.00035/full
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