MAP Kinase Phosphatase 3 (MKP3) Preserves Norepinephrine Transporter Activity by Modulating ERK1/2 Kinase-Mediated Gene Expression

The norepinephrine transporter (NET) mediates the clearance of norepinephrine (NE) from the extracellular space and is a target of therapeutic antidepressants and psychostimulants. Previously we identified a MAP kinase phosphatase 3 (MKP3), as an important modulator of protein kinase C (PKC) mediate...

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Principais autores:	Ole V. Mortensen, Mads B. Larsen, Susan G. Amara
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2017-08-01
coleção:	Frontiers in Cellular Neuroscience
Assuntos:	caveolin dual-specificity phosphoprotein phosphatase extracellular-signal-regulated kinase (ERK) mitogen-activated protein kinase (MAPK) monoamine transporter norepinephrine
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fncel.2017.00253/full
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