Obesity Increases Mitogen-Activated Protein Kinase Phosphatase-3 Levels in the Hypothalamus of Mice

Mitogen-activated Protein Kinase Phosphatase 3 (MKP-3) has been involved in the negative regulation of insulin signaling. The absence of MKP-3 is also associated with reduced adiposity, increased energy expenditure and improved insulin sensitivity. The MKP-3 is known as the main Erk1/2 phosphatase a...

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Principais autores:	Bárbara de A. Rodrigues, Vitor R. Muñoz, Gabriel K. Kuga, Rafael C. Gaspar, Susana C. B. R. Nakandakari, Barbara M. Crisol, José D. Botezelli, Luciana S. S. Pauli, Adelino S. R. da Silva, Leandro P. de Moura, Dennys E. Cintra, Eduardo R. Ropelle, José R. Pauli
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2017-10-01
Series:	Frontiers in Cellular Neuroscience
Assuntos:	MKP-3 insulin hypothalamus obesity food intake
Acceso en liña:	http://journal.frontiersin.org/article/10.3389/fncel.2017.00313/full
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